Independence of tumor necrosis factor-α-induced adhesion molecule expression from sphingosine 1-phosphate signaling in vascular endothelial cells
✍ Scribed by Y. Miura; Y. Yatomi; T. Ohmori; M. Osada; Y. Ozaki
- Book ID
- 109148369
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 357 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1538-7933
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## Abstract ## Objective To investigate the roles of MAPKs and NF‐κB in tumor necrosis factor α (TNFα)–induced expression of vascular cell adhesion molecule 1 (VCAM‐1) in human rheumatoid arthritis synovial fibroblasts (RASFs). ## Methods Human RASFs were isolated from synovial tissue obtained f
Adhesion molecules such as intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) have been implicated in the pathogenesis of various inflammatory liver disease states, including viral and autoimmune hepatitis as well as liver allograft rejection. Tumor necrosis fa