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S1P2 receptor mediates sphingosine-1-phosphate-induced fibronectin expression via MAPK signaling pathway in mesangial cells under high glucose condition

✍ Scribed by Weihua Liu; Tian Lan; Xi Xie; Kaipeng Huang; Jing Peng; Juan Huang; Xiaoyan Shen; Peiqing Liu; Heqing Huang


Book ID
113956204
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
944 KB
Volume
318
Category
Article
ISSN
0014-4827

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## Abstract Sphingosine 1‐phosphate (S1P) has been shown to regulate smooth muscle cell proliferation, migration, and vascular maturation. S1P increases the expression of several proteins including COX‐2 in vascular smooth muscle cells (VSMCs) and contributes to arteriosclerosis. However, the mecha