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Sphingosine 1-phosphate and lysophosphatidic acid receptors: agonist and antagonist binding and progress toward development of receptor-specific ligands

✍ Scribed by Abby L Parrill; Vineet M Sardar; Hongbin Yuan


Book ID
117983903
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
233 KB
Volume
15
Category
Article
ISSN
1084-9521

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Lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) are potent phospholipid mediators with diverse biological activities. Their appearance and functional properties suggest possible roles in development, wound healing, and tissue regeneration. The growth-stimulating and other complex biolo