Lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) are potent phospholipid mediators with diverse biological activities. Their appearance and functional properties suggest possible roles in development, wound healing, and tissue regeneration. The growth-stimulating and other complex biolo
Molecular Identification and Characterization of G Protein-Coupled Receptors for Lysophosphatidic Acid and Sphingosine 1-Phosphate
β Scribed by SONGZHU AN
- Book ID
- 111396457
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 207 KB
- Volume
- 905
- Category
- Article
- ISSN
- 0890-6564
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## Abstract The lysophospholipid growth factors sphingosine 1βphosphate (S1P) and lysophosphatidic acid (LPA) are generated by many cells involved in immunity, including macrophages, dendritic cells, mast cells, and platelets, with resultant lymph and plasma concentrations of 0.1β1 ΞΌM. All immune c
## Abstract Lysophosphatidic acid (LPA) and sphingosineβ1βphosphate (S1P) have been proposed to play a key role in oligodendrocyte maturation and myelinogenesis. In this study, we examined lysophospholipid receptor gene expression in differentiated rat oligodendrocyte cultures and signaling downstr