Using the hamster oocyte/human sperm fusion technique, we studied sperm chromosome complements in two male reciprocal translocation heterozygotes, 46,XY,t(11;17)(p11.2;q12.3) and 46,XY,t(1;11) (p36.3;q13.1). For the t(11;17) carrier, 202 sperm chromosome complements were obtained, but 18 karyotypes
Sperm chromosome complements from two human reciprocal translocation heterozygotes
β Scribed by Elizabeth L. Spriggs; Renee H. Martin; Maj Hulten
- Publisher
- Springer
- Year
- 1992
- Tongue
- English
- Weight
- 27 KB
- Volume
- 90
- Category
- Article
- ISSN
- 0340-6717
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Sperm chromosome complements from two males, one heterozygous for the reciprocal translocation t(2;17)(q35;p13) (n = 18) and one for t(3;8) (p13;p21) (n = 73), were analyzed. Only 2:2 segregations were observed with t(2;17): alternate, 56%; adjacent-I, 33%; adjacent-II, 11%. Both 2:2 and 3:1 meiotic
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