𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Human sperm chromosome studies in a reciprocal translocation t(2;5)

✍ Scribed by Cristina Templado; Joaquima Navarro; Jordi Benet; Anna Genescà; M. Mar Pérez; José Egozcue

Publisher
Springer
Year
1988
Tongue
English
Weight
924 KB
Volume
79
Category
Article
ISSN
0340-6717

No coin nor oath required. For personal study only.

✦ Synopsis

Sperm chromosome complements have been studied in a man heterozygous for a reciprocal translocation t(2;5)(p11;q15). Human sperm chromosomes were obtained after fertilization of zona-free hamster eggs. A total of 75 human sperm metaphases were analysed. On the complements studied, 59 (78.6%) resulted from a 2:2 segregation and 16 (21.3%) from a 3:1 segregation, 4:0 segregation was not observed. Our results indicate that at least 36% of sperm complements were unbalanced with respect to the translocation. The frequency of other chromosome anomalies unrelated to the translocation was 16%.

📜 SIMILAR VOLUMES

Sperm chromosome analysis of two males h
Sperm chromosome analysis of two males heterozygous for a t(2;17)(q35;p13) and t(3;8)(p13;p21) reciprocal translocation
✍ J. Jenderny 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 315 KB

Sperm chromosome complements from two males, one heterozygous for the reciprocal translocation t(2;17)(q35;p13) (n = 18) and one for t(3;8) (p13;p21) (n = 73), were analyzed. Only 2:2 segregations were observed with t(2;17): alternate, 56%; adjacent-I, 33%; adjacent-II, 11%. Both 2:2 and 3:1 meiotic