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Spectroscopic investigation of Rose Bengal/cyclodextrin interactions in aqueous solution: the case of the hydroxypropyl-cyclodextrins

โœ Scribed by P. Fini; L. Catucci; M. Castagnolo; P. Cosma; V. Pluchinotta; A. Agostiano


Book ID
106388918
Publisher
Springer Netherlands
Year
2007
Tongue
English
Weight
295 KB
Volume
57
Category
Article
ISSN
0923-0750

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The interaction between spironolactone (Sp) and hydroxypropyl-b-cyclodextrin (HPbCD) has been investigated in aqueous solution and in the solid state. Phase solubility studies indicate that the complex is formed with possible stoichiometry of 1:1 and association constant of 9806 M ร€1 . Differential