The inclusion complex formation of alpha-cyclodextrin (alpha-CyD), beta-cyclodextrin (beta-CyD), and 2-hydroxylpropyl-beta-cyclodextrin (HP-beta-CyD) with an angiotensin converting enzyme inhibitor, captopril, in aqueous solution was studied by (1)H- and (13)C-nuclear magnetic resonance spectroscopi
Investigation of the β-cyclodextrin-quinine inclusion complex in aqueous solution by spectroscopic study
✍ Scribed by Xue-Mei Wang; Hong-Yuan Chen
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 367 KB
- Volume
- 51
- Category
- Article
- ISSN
- 1386-1425
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## Abstract ^1^H NMR spectroscopic study of midazolam hydrochloride (MDL), β‐cyclodextrin (β‐CD) and their mixtures confirmed the formation of β‐CD‐MDL inclusion complex in aqueous solution. The stoichiometry of the complexes was determined by Scott's method to be 1:1, and the association constant