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Spectroscopic characterization of 13-cis- and all-trans-retinamides

✍ Scribed by Coburn, William C.; Thorpe, Martha C.; Shealy, Y. Fulmer; Kirk, Marion C.; Frye, Jerry L.; O'Dell, C. Allen


Book ID
121273485
Publisher
American Chemical Society
Year
1983
Tongue
English
Weight
810 KB
Volume
28
Category
Article
ISSN
0021-9568

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Effect of 13-cis-retinoic acid and 4-hyd
✍ Frank L. Meyskens Jr.; David S. Alberts; Sydney E. Salmon πŸ“‚ Article πŸ“… 1983 πŸ› John Wiley and Sons 🌐 French βš– 498 KB πŸ‘ 1 views

## Abstract We studied the effects of 13‐cis‐retinoic acid (13cRA) and 4‐hydroxyphenyl‐all‐trans‐retinamide (4HPR) on the proliferation of clonogenic human tumor colony‐forming units (TCFU) from patient biopsies in soft agar. Continuous exposure (5 Γ— 10^βˆ’6^M) to 13cRA and 4HPR reduced colony format