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Specific JAK2 mutation (JAK2R683) and multiple gene deletions in Down syndrome acute lymphoblastic leukemia

✍ Scribed by Kearney, L.; Gonzalez De Castro, D.; Yeung, J.; Procter, J.; Horsley, S. W.; Eguchi-Ishimae, M.; Bateman, C. M.; Anderson, K.; Chaplin, T.; Young, B. D.; Harrison, C. J.; Kempski, H.; Wai E. So, C.; Ford, A. M.; Greaves, M.


Book ID
121681386
Publisher
American Society of Hematology
Year
2009
Tongue
English
Weight
285 KB
Volume
113
Category
Article
ISSN
0006-4971

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## Abstract Previous cytogenetic studies of myeloid and acute lymphoblastic leukemias in children with Down syndrome (ML‐DS and DS‐ALL) have revealed significant differences in abnormality patterns between such cases and acute leukemias in general. Also, certain molecular genetic aberrations charac