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Specific detection of anti-idiotypic immune responses in cancer patients treated with murine monoclonal antibody

โœ Scribed by Dorothee Herlyn; Michael Lubeck; Henry Sears; Hilary Koprowski

Book ID
118899915
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
633 KB
Volume
85
Category
Article
ISSN
0022-1759

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## Abstract A human monoclonal antiโ€idiotypic antibody (105AD7) has been developed which mimics a colorectalโ€tumourโ€associated antigen and induces cellular antiโ€colorectal tumour immune responses in animals. Thirteen patients with advanced colorectal cancer were immunized with 105AD7 and their surv