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Human anti-murine antibody responses in ovarian cancer patients undergoing radioimmunotherapy with the murine monoclonal antibody OC-125

✍ Scribed by Michael G. Muto; Neil J. Finkler; Amin I. Kassis; Eva Marie Lepisto; Robert C. Knapp


Book ID
119053459
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
463 KB
Volume
38
Category
Article
ISSN
0090-8258

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Monoclonal antibody (MAb) O C 125 binds to approximately 80% of epithelial ovarian cancers. Serum antigen, CAI25, can be detected in these patients. "'I-OC 125-F(ab')2 was injected into 5 ovarian carcinoma patients with preinjection serum levels of I50 to 9,000 CAI25 U/ml. Patients received the anti