## Abstract ## Objective Recent data have shown that the most prominent and longest known genetic risk factors for rheumatoid arthritis (RA), HLA–DRB1 shared epitope alleles, are only associated with RA that is characterized by the presence of antibodies against cyclic citrullinated peptide (anti‐
Specific association of type 1 diabetes mellitus with anti–cyclic citrullinated peptide–positive rheumatoid arthritis
✍ Scribed by Katherine P. Liao; Marie Gunnarsson; Henrik Källberg; Bo Ding; Robert M. Plenge; Leonid Padyukov; Elizabeth W. Karlson; Lars Klareskog; Johan Askling; Lars Alfredsson
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 131 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0004-3591
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## Abstract ## Objective Anti–cyclic citrullinated peptide (anti‐CCP) antibodies are rheumatoid arthritis (RA)–specific serologic markers. RA susceptibility has been associated with HLA–DRB1 shared epitope (SE) alleles and single‐nucleotide polymorphism (SNP) haplotypes in the peptidyl arginine de
## Abstract ## Objective To examine the association of treatment response and disease duration with changes in rheumatoid factor (RF) and anti–cyclic citrullinated peptide (anti‐CCP) antibody levels among patients with rheumatoid arthritis (RA). ## Methods The study sample included 66 RA patient