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Protection against anti–citrullinated protein antibody–positive rheumatoid arthritis is predominantly associated with HLA–DRB1*1301: A meta-analysis of HLA–DRB1 associations with anti–citrullinated protein antibody–positive and anti–citrullinated protein antibody–negative rheumatoid arthritis in four European populations

✍ Scribed by Diane van der Woude; Benedicte A. Lie; Emeli Lundström; Alejandro Balsa; Anouk L. Feitsma; Jeanine J. Houwing-Duistermaat; Willem Verduijn; Gry B. N. Nordang; Lars Alfredsson; Lars Klareskog; Dora Pascual-Salcedo; Miguel A. Gonzalez-Gay; Miguel A. Lopez-Nevot; Fernando Valero; Bart O. Roep; Tom W. J. Huizinga; Tore K. Kvien; Javier Martín; Leonid Padyukov; René R. P. de Vries; René E. M. Toes


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
154 KB
Volume
62
Category
Article
ISSN
0004-3591

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✍ Bo Ding; Leonid Padyukov; Emeli Lundström; Mark Seielstad; Robert M. Plenge; Jor 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 386 KB 👁 2 views

## Abstract ## Objective To identify additional variants in the major histocompatibility complex (MHC) region that independently contribute to risk in 2 disease subsets of rheumatoid arthritis (RA) defined according to the presence or absence of antibodies to citrullinated protein antigens (ACPAs)