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Species-specific protein sequence and fold optimizations

✍ Scribed by Michel Dumontier; Katerina Michalickova; Christopher WV Hogue


Book ID
114999639
Publisher
BioMed Central
Year
2002
Tongue
English
Weight
506 KB
Volume
3
Category
Article
ISSN
1471-2105

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The role of local interactions in protein folding has recently been the subject of some controversy. Here we investigate an extension of Zwanzig's simple and general model of folding in which local and nonlocal interactions are represented by functions of single and multiple conformational degrees o