Defective growth in vitro of Duchenne mu
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Mariarosa A.B. Melone; Gianfranco Peluso; Orsolina Petillo; Umberto Galderisi; R
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Article
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2000
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John Wiley and Sons
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English
β 234 KB
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As the molecular basis of Duchenne Muscular Dystrophy (DMD) was being discovered, increasing focus was placed on the mechanisms of progressive failure of myoregeneration. In this study, we propose a pathogenesis model for DMD, where an autocrine growth factor release of TGF-β€1-from necrotic myofiber