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Spatial organization of three-dimensional cocultures of adriamycin-sensitive and -resistant human breast cancer MCF-7 cells

โœ Scribed by A Starzec; D Briane; M Kraemer; J.-C Kouyoumdjian; J.-L Moretti; R Beaupain; O Oudar


Book ID
114191881
Publisher
Portland Press
Year
2003
Tongue
English
Weight
508 KB
Volume
95
Category
Article
ISSN
0248-4900

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In this study the ability of the new pure anti-estrogen IcI 182,780 to modulate the cytotoxic action of adriamycin (ADR) on parental and ADR-resistant MCF-7 (MCF-7 ADRr) human breast-cancer cells was investigated and compared with that of tamoxifen (TAM). TAM enhanced ADR cytotoxicity in MCF-7 ADRr