𝔖 Bobbio Scriptorium
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Sparged Animal Cell Bioreactors: Mechanism of Cell Damage and Pluronic F-68 Protection

✍ Scribed by David W. Murhammer; Charles F. Goochee


Book ID
114420443
Publisher
American Institute of Chemical Engineers
Year
1990
Tongue
English
Weight
930 KB
Volume
6
Category
Article
ISSN
8756-7938

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## Abstract The surfactant Pluronic F‐68 (PF‐68) is widely used in large‐scale mammalian cell culture to protect cells from shear stress that arises from agitation and gas sparging. Several studies suggested that PF‐68 is incorporated into the cell plasma membrane and could enter the cells, but wit