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Quantitative Studies of Cell-Bubble Interactions and Cell Damage at Different Pluronic F-68 and Cell Concentrations

✍ Scribed by Ningning Ma; Jeffery J. Chalmers; John G. Auniņš; Weichang Zhou; Liangzhi Xie

Book ID
109386913
Publisher
American Institute of Chemical Engineers
Year
2004
Tongue
English
Weight
189 KB
Volume
20
Category
Article
ISSN
8756-7938

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## Abstract It is well known that bubble rupture has a detrimental effect on mammalian cells. As a result, Pluronic F‐68 (PF‐68), a nonionic surfactant, is commonly used to reduce bubble‐associated cell damage in sparged bioreactors. While PF‐68 is currently effective, there is a concern with respe