𝔖 Bobbio Scriptorium
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SP025 Genotype-based combinations of RAS/RAF and PI3K pathway inhibitors

✍ Scribed by Banerji, U.


Book ID
122233010
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
49 KB
Volume
49
Category
Article
ISSN
0959-8049

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## Abstract While M‐CSF‐mediated MEK/ERK activation promotes osteoclast survival, the signaling pathway by which M‐CSF activates MEK/ERK is unresolved. Functions for PI3K, Ras, and Raf have been implicated in support of osteoclast survival, although interaction between these signaling components ha