## Abstract __Intercalating nucleic acids (INAยฎs) with insertions of (__R__)โ1โ__O__โ(1โpyrenylmethyl)glycerol were hybridized with locked nucleic acids (LNAs). INA/LNA duplexes were found to be less stable than the corresponding DNA/LNA duplexes when the INA monomer was inserted as a bulge close t
Some recent studies on the composition and structure of nucleic acids
โ Scribed by Chargaff, Erwin
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1951
- Tongue
- English
- Weight
- 712 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0095-9898
No coin nor oath required. For personal study only.
โฆ Synopsis
The first question that must be answered before the determination of the structure of nucleic acids can be carried out in earnest is: how much of what do they contain? It seemed to us that procedures suitable for this purpose had been lacking in the past and that no real progress was possible, unless the necessary analytical groundwork was laid. Following the demonstration that the excellent method of chromatography on filter paper (Consden, Gordon and Martin, '44) could be applied t o the separation of purines (Vischer and Chargaff, '47), procedures for the separation, in minute amounts, of the nitrogenous nucleic acid constituents and for their identification and quantitative estimation by spectrophotometry were elaborated (purines and pyrimidines :
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## Abstract Structural composition of two distillate waxes obtained from Ankleshwar crude oil tank bottoms have been determined using physical properties correlations, high temperature g.l.c., ^1^Hโn.m.r. and ^13^CโFourier transform n.m.r. spectroscopy. Both waxes seem to contain predominantly nโpa