Recent Synthetic Studies on the Zaragozic Acids (Squalestatins)
β Scribed by Alan Armstrong; Toby J. Blench
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 73 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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## Abstract The pseudo __C__~2~βsymmetrical diketone **22** was efficiently constructed from furanβ3,4βdimethanol (**7**) using a twoβdirectional route featuring a double asymmetric dihydroxylation. Acidic hydrolysis of the cyclopentylidene acetals of **22** triggered a selective cyclization of the
Evaluation of Furan Photooxygenation as a Device for Construction of the Zaragozic Acid (Squalestatin) Core. -The photooxygenation of compound (IX) allows the stereocontrolled construction of the title core (X) starting from (I) in seven steps. -(MAEZAKI, N.; GIJSEN, H.