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Some Reactions of Amino Acid N-Carboxy Anhydrides

✍ Scribed by Kopple, Kenneth D.


Book ID
120445646
Publisher
American Chemical Society
Year
1957
Tongue
English
Weight
653 KB
Volume
79
Category
Article
ISSN
0002-7863

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## Abstract Oligopeptides were synthesized in high yields by the controlled coupling reaction of __N__‐carboxy α‐amino acid anhydrides (NCA's) with amino acid and peptide sodium salts in the heterogeneous reaction medium of acetonitrile–water which contained sodium carbonate. In this solvent, it co