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Some nitration properties of 1-methylpyrazoles

✍ Scribed by V. P. Perevalov; Yu. A. Manaev; L. I. Baryshnenkova; B. I. Stepanov


Book ID
104781984
Publisher
Springer US
Year
1988
Tongue
English
Weight
80 KB
Volume
24
Category
Article
ISSN
0009-3122

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The nitration of pyridine l-oxide to give 4-nitropyridine l-oxide is a reaction of great practical and theoretical interest.1 Carried out in aulphuric acid, the reaction involves the free base. The availability of l-methylpyrazole 2-oxide2 made it of interest to examine the orientation of nitration

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## Abstract The major products from the reaction of β‐alkoxyvinyl trifluoromethyl ketones **1a‐c** with methylhydrazine (**2**) in absolute ethanol are the 3‐(trifluoromethyl)‐substituted‐1‐methylpyrazoles **3a‐3c** with lesser amounts of the 5‐(trifluoromethyl)‐substituted products **4a‐4c** and *