The nitration of 1-methylpyrazole 2-oxide

✍ Scribed by I.J. Ferguson; M.R. Grimmett; K. Schofield

• Book ID: 104236840
• Publisher: Elsevier Science
• Year: 1972
• Tongue: French
• Weight: 87 KB
• Volume: 13
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)84929-7

✦ Synopsis

The nitration of pyridine l-oxide to give 4-nitropyridine l-oxide is a reaction of great practical and theoretical interest.1 Carried out in aulphuric acid, the reaction involves the free base. The availability of l-methylpyrazole 2-oxide2 made it of interest to examine the orientation of nitration of this compound and to study the mechanism of the reaction.