Profile analysis using capillary gas chromatography is applied in clinical chemistry to detect metabolic abnormalities. Examples are the increase of the urinary excretion of aromatic acids carrying a 4-hydroxyl group and the decrease of hippuric acid in liver cirrhosis, and the elevated concentratio
Some applications of capillary gas chromatography in the chemical industry
β Scribed by van Straten, A. J.
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 305 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0935-6304
No coin nor oath required. For personal study only.
β¦ Synopsis
About three years ago, fused silica capillary columns were introduced in the Quality Control Laboratory of the Shell refinery/chemical complex at Pernis. In general, long, thick-film, wide-bore capillary columns are used together with low split ratios and hydrogen as carrier gas. These conditions enable the analysis of relatively large sample amounts, resulting in low detection limits for the minor components without overloading by the major components, while still maintaining a satisfactory resolution. A number of applications are shown, such as the analysis of complex mixtures, the determination of trace impurities and the analysis of residual volatiles in polymers.
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