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Somatostatin analogs: angiogenesis inhibitors with novel mechanisms of action

✍ Scribed by Eugene A. Woltering; James C. Watson; R. Christian Alperin-Lea; Chakravarthi Sharma; Edward Keenan; Daryl Kurozawa; Rosemary Barrie


Book ID
110229112
Publisher
Springer US
Year
1997
Tongue
English
Weight
149 KB
Volume
15
Category
Article
ISSN
0167-6997

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Carbonic anhydrase inhibitors: possible
✍ Claudiu T. Supuran πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 164 KB

## Abstract The tumor‐associated carbonic anhydrase (CA, EC 4.2.1.1) isozyme CA IX is highly overexpressed in many cancer types via the hypoxia inducible factor‐1Ξ± (HIF‐1Ξ±) cascade. Hypoxic tumors expressing CA IX show a poor response to classical chemo‐ and radio‐therapy treatments. CA IX signific