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Primary Therapy for Acromegaly with Somatostatin Analogs and a Discussion of Novel Peptide Analogs

✍ Scribed by David L. Kleinberg

Book ID
106515823
Publisher
Springer
Year
2005
Tongue
English
Weight
326 KB
Volume
6
Category
Article
ISSN
1389-9155

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Metastable fragmentation of somatostatin
Metastable fragmentation of somatostatin-14 (SS-14) and a series of SS-14 analogs formed with liquid secondary ion mass spectrometry: Observation of fragment ions which involve unsymmetric disulfide bridge cleavage concomitant with peptide chain cleavage
✍ A. Grey Craig; Jean E. Rivier πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 916 KB

Somatostatin-14 (SS-14) and several SS-14 analogs were analyzed using liquid secondary ion mass spectrometry (LSIMS). The observed isotope distributions showed low levels of [ H,-SS-14] (reduced SS-14). The daughter-ion spectra of the protonated molecule ions of SS-14 and several SS-14 analogs conta