𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Glibenclamide: an old drug with a novel mechanism of action?

✍ Scribed by L. Luzi; G. Pozza

Book ID
106194494
Publisher
Springer
Year
1997
Tongue
English
Weight
153 KB
Volume
34
Category
Article
ISSN
0940-5429

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Anti-tumor mechanisms of valproate: A no
Anti-tumor mechanisms of valproate: A novel role for an old drug
✍ Roman A. Blaheta; Jindrich Cinatl Jr. πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 175 KB

Valproic acid (VPA, 2-propylpentanoic acid) is an established drug in the long-term therapy of epilepsy. During the past years, it has become evident that VPA is also associated with anti-cancer activity. VPA not only suppresses tumor growth and metastasis, but also induces tumor differentiation in

Carbonic anhydrase inhibitors: possible
Carbonic anhydrase inhibitors: possible anticancer drugs with a novel mechanism of action
✍ Claudiu T. Supuran πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 164 KB

## Abstract The tumor‐associated carbonic anhydrase (CA, EC 4.2.1.1) isozyme CA IX is highly overexpressed in many cancer types via the hypoxia inducible factor‐1Ξ± (HIF‐1Ξ±) cascade. Hypoxic tumors expressing CA IX show a poor response to classical chemo‐ and radio‐therapy treatments. CA IX signific