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Antitumor Mechanisms of Valproate: A Novel Role for an Old Drug

โœ Scribed by Roman A. Blaheta; Jindrich Cinatl Jr.

Publisher
John Wiley and Sons
Year
2010
Weight
25 KB
Volume
33
Category
Article
ISSN
0931-7597

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Anti-tumor mechanisms of valproate: A no
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Valproic acid (VPA, 2-propylpentanoic acid) is an established drug in the long-term therapy of epilepsy. During the past years, it has become evident that VPA is also associated with anti-cancer activity. VPA not only suppresses tumor growth and metastasis, but also induces tumor differentiation in

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A novel drug delivery system possessing prolonged release behavior is introduced to the field of carrier erythrocytes and nanotechnology-based drug delivery. Encapsulation of valproate-loaded nanogels inside human erythrocytes as a novel nanocell composite was the objective of the study to obtain a