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Somatic mutations of mitochondrial DNA in aging and cancer progression

✍ Scribed by Hsin-Chen Lee; Chia-Ming Chang; Chin-Wen Chi

Book ID
116255345
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
570 KB
Volume
9
Category
Article
ISSN
1872-9649

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## Abstract Exciting new studies are increasingly strengthening the link between mitochondrial mutagenesis and tumor progression. Here we provide a comprehensive review and meta‐analysis of studies reporting on mitochondrial DNA mutations in common human cancers. We discuss possible mechanisms by w