✦ LIBER ✦

Mitochondrial DNA mutations in disease and aging

✍ Scribed by Douglas C. Wallace

Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 148 KB
Volume: 51
Category: Article
ISSN: 0893-6692
DOI: 10.1002/em.20586

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Mitochondrial DNA mutations in human dis

Mitochondrial DNA mutations in human disease

✍ DiMauro, Salvatore ;Schon, Eric A. 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 182 KB 👁 2 views

Mitochondrial DNA mutations and mitochon

Mitochondrial DNA mutations and mitochondrial DNA depletion in gastric cancer

✍ Chew-Wun Wu; Pen-Hui Yin; Wen-Yi Hung; Anna Fen-Yau Li; Shu-Hui Li; Chin-Wen Chi 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 308 KB 👁 1 views

## Abstract Gastric carcinoma is one of the most common types of cancer in Taiwan. Somatic mitochondrial DNA (mtDNA) alteration in gastric carcinoma and its association with clinicopathologic features remain unclear. When we used polymerase chain reaction (PCR) and direct sequencing, 15 of the 31 (

Mitochondrial DNA mutations and mitochon

Mitochondrial DNA mutations and mitochondrial DNA depletion in breast cancer

✍ Ling-Ming Tseng; Pen-Hui Yin; Chin-Wen Chi; Chih-Yi Hsu; Chew-Wun Wu; Liang-Ming 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 206 KB 👁 1 views

## Abstract Somatic mutations in mitochondrial DNA (mtDNA) have been demonstrated in various tumors, including breast cancer. However, it still remains unclear whether the alterations in mtDNA are related to the clinicopathological features and/or the prognosis in the breast cancer. We analyzed som

Detection of mitochondrial DNA mutations

Detection of mitochondrial DNA mutations in gestational trophoblastic disease

✍ Pui Man Chiu; Vincent W.S. Liu; Hextan Y.S. Ngan; Ui Soon Khoo; Annie N.Y. Cheun 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 188 KB

Mitochondrial DNA (mtDNA) mutations have been implicated in a wide range of human disease. However, its role in gestational trophoblastic disease remains unclear. In this study, the entire mitochondrial genome of 10 hydatidiform moles (HM) and one choriocarcinoma were examined by automated DNA seque

Differential occurrence of mutations in

Differential occurrence of mutations in mitochondrial DNA of human skeletal muscle during aging

✍ Chunfang Zhang; Vincent W. S. Liu; Corrado L. Addessi; David A. Sheffield; Antho 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 305 KB 👁 2 views

## Communicated by Henrik Dahl Seven mtDNA mutations (five base substitutions and two deletions) were studied in skeletal muscle samples of 18 human subjects aged 1 hr to 90 years. Quantitative PCR procedures were applied to determine the incidence (frequency of occurrence) and abundance (percentag

Microsatellite instability, mitochondria

Microsatellite instability, mitochondrial DNA large deletions, and mitochondrial DNA mutations in gastric carcinoma

✍ Valdemar Máximo; Paula Soares; Raquel Seruca; Ana Sofia Rocha; Patrícia Castro; 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 118 KB 👁 1 views

## Abstract Mitochondrial DNA (mtDNA) large deletions and mtDNA mutations have been demonstrated in various types of human cancer. The relationship between the occurrence of such alterations and the nuclear microsatellite instability (MSI) status of the neoplastic cells remains controversial. In an