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Somatic mutation in autoantibody-associated VH genes of circulating IgM+IgD+ B cells

✍ Scribed by Yasuhiko Munakata; Shin-ichiro Saito; Atsushi Hoshino; Tai Muryoi; Yasuhiko Hirabayashi; Shinobu Shibata; Toshihiko Miura; Tomonori Ishii; Tadao Funato; Takeshi Sasaki


Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
240 KB
Volume
28
Category
Article
ISSN
0014-2980

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Human IgM+IgD+ B cells, the major B cell
✍ Ulf Klein; Ralf KΓΌppers; Klaus Rajewsky πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 606 KB

## life* Peripheral blood B cells of a 67-year-old person were separated into IgM+IgD+, IgM+IgD-, and IgM-IgD-subsets, and nucleotide sequences of expressed immunoglobulin light chain variable (V) regions encoded by V,3 and V,4 gene family members were determined from amplified cDNA. V region sequ