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Analysis of expressed VH genes in persistent polyclonal B cell lymphocytosis reveals absence of selection in CD27+IgM+IgD+ memory B cells

✍ Scribed by Marguerite Massinga Loembé; Sonia Néron; Robert Delage; André Darveau


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
233 KB
Volume
32
Category
Article
ISSN
0014-2980

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## Abstract ## Objective Analysis of peripheral B cell subsets in patients with systemic lupus erythematosus (SLE) has provided evidence of specific alterations, such as an expansion of CD27++ plasma cells/blasts and transitional B cells. However, memory B cells in lupus have not been thoroughly i