Somatic Hypermutations in the VHSegment of Immunoglobulin Genes of CDS-positive Diffuse Large B-Cell Lymphomas
β Scribed by Kume, Masaaki ;Suzuki, Ritsuro ;Yatabe, Yasushi ;Kagami, Yoshitoyo ;Miura, Ikuo ;Miura, Akira B. ;Morishima, Yasuo ;Nakamura, Shigeo ;Seto, Masao
- Book ID
- 108581365
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1997
- Tongue
- English
- Weight
- 412 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0910-5050
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The prognosis of diffuse large Bβcell lymphoma (DLBCL) has improved markedly in recent years of rituximab era. The prognosis of __de novo__ CD5βpositive DLBCL is reported to be poor, but the effect of rituximab on this type of lymphoma remains unclear. To investigate the effect of ritux
The sequence of the exon I lintron I boundary region of the MYC gene was determined in two diffuse large cell lymphomas (DLCL), one with t(8; 14) (q24q32) and the other with t(8;22) (q24;q I I). Both tumors had multiple mutations in this region. Also, both tumors had mutations in the protein binding
## Abstract Diffuse large Bβcell lymphomas (DLBCL) are highly heterogeneous with regard to clinical presentation and outcome. DLBCL copy number aberrations have been identified previously, of which the deletion at 6q21β24 was significantly associated with a highly favorable clinical response to che