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Somatic BRCA1 tumorigenesis in sporadic breast and ovarian cancer

✍ Scribed by M.J.W. Van der Looij; J. Papp; P. Devilee; E. Oláh

Book ID
117658498
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
164 KB
Volume
37
Category
Article
ISSN
0959-8049

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The genetic changes underlying the development and progression of male breast cancer are poorly understood. Germline BRCA2 mutations account for a significant part of male breast cancer, but the majority of patients lack a known inherited predisposition. We recently demonstrated that the progression