Soluble protein encoded by CD44 variant exons 8–10 in the serum of patients with colorectal cancer
✍ Scribed by Dr T. Goi; A. Yamaguchi; K. Seki; G. Nakagawara; T. Urano; H. Shiku; K. Furukawa
- Book ID
- 108677593
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 155 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0007-1323
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In a recent paper published in this journal [l], the authors measured the expression of CD44 isoforms in four human prostate tumor cell lines by flow cytometric analysis, Western blot, and at the mRNA level by reverse transcription polymerase chain reaction. The results showed that CD44 isoforms wer
CD44 is a widely expressed cell surface adhesion molecule in which various isoforms arise from alternative RNA splicing mechanism. Overexpression of specific CD44 splice variant, i.e., CD44v8-10, has been found in several human malignancies and is considered to be associated with tumor progression a