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Soluble CD44 v5 and v6 in serum of patients with breast cancer. Correlation with expression of CD44 v5 and v6 variants in primary tumors and location of distant metastasis

✍ Scribed by Carolin Lackner; Renate Moser; Thomas Bauernhofer; Martie Wilders-Truschnig; Hellmut Samonigg; Andrea Berghold; Kurt Zatloukal


Book ID
110230407
Publisher
Springer US
Year
1998
Tongue
English
Weight
302 KB
Volume
47
Category
Article
ISSN
0167-6806

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In the present study, the expression and prognostic role of the CD44 splicing variants v5 and v6 were immunohistochemically investigated in 418 curatively resected gastric carcinomas. CD44v5 was expressed in 65β€’3 per cent (n=273) and CD44v6 in 77β€’0 per cent (n=322) of the tumours. Whereas the expres

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Expression of CD44 and its variants is associated with clinically aggressive behavior of some human cancers. The present study was undertaken to determine the expression level of these CD44 mRNAs in relation to the clinicopathologic features and prognosis of gastric cancer. Using reverse transcripti