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Solubilization and hydrodynamic characteristics of the erythropoietin receptor : Evidence for a multimeric complex

✍ Scribed by Patrick MAYEUX; Nicole CASADEVALL; Catherine LACOMBE; Odile MULLER; Pierre TAMBOURIN


Book ID
115128291
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
992 KB
Volume
194
Category
Article
ISSN
1432-1327

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A partial model of the erythropoietin re
✍ Caravella, Justin A.; Lyne, Paul D.; Richards, W. Graham πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 836 KB

A model of the structure of erythropoietin (Epo) is presented based on structural homology to other hemopoietic cytokines. A model of the erythropoietin receptor complex w a s made based on evidence that this includes a homodimer of the receptor chain with known sequence. Key interactions are noted