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Erythropoietin induces the association of phosphatidylinositol 3′-kinase with a tyrosine-phosphorylated protein complex containing the erythropoietin receptor

✍ Scribed by Patrick MAYEUX; Isabelle DUSANTER-FOURT; Odile MULLER; Philippe MAUDUIT; Michèle SABBAH; Brian DRUKER; William VAINCHENKER; Sigmund FISCHER; Catherine LACOMBE; Sylvie GISSELBRECHT


Book ID
115130241
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
869 KB
Volume
216
Category
Article
ISSN
1432-1327

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✍ Ashok R. Venkitaraman; Rachel J. Cowling 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 856 KB

## Abstract The recently characterized receptor for interleukin (IL)‐7 (IL‐7R) includes a unique α chain as well as a common γ chain shared with the receptors for IL‐2 and IL‐4. Engagement of the IL‐7R activates the intracellular enzyme phosphatidylinositol (PtdIns) 3‐kinase but the mechanism of Pt