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Solubility and dissolution enthalpy of xanthine

✍ Scribed by Erich Königsberger; Zhonghua Wang; Jürgen Seidel; Gert Wolf

Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
118 KB
Volume
33
Category
Article
ISSN
0021-9614

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✦ Synopsis

At a constant ionic strength corresponding to human urine (I c = 0.300 mol • dm -3 ), the solubilities of xanthine were measured as a function of

) at the temperatures T = 298.15 K and T = 310.15 K, respectively. Highly reproducible solubility and dissociation constants were obtained. Also, for the first time, the dissolution enthalpy of xanthine was determined calorimetrically. The values of this quantity obtained from both calorimetric determination and temperature dependence of solubility equilibrium constants are thermodynamically consistent.

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