Solid supports for combinatorial chemistry
β Scribed by Zhanru Yu; Mark Bradley
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 193 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1367-5931
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π SIMILAR VOLUMES
Enantiopure C2-symmetric azepanes have been synthesized on solid support as scaffolds for the synthesis of peptidomimetics in combinatorial chemistry. The key step involves Rink resin as a formal equivalent of ammonia in the nucleophilic opening of L-iditol bis-epoxide.
A scintillant monomer, 2,5-diphenyl-4-vinyloxazole, has been synthesised and co-polymerised with 4ethylstyrene, divinylbenzene and 4-vinylbenzyl chloride in the presence of a toluene porogen, to form a scintillant-containing macroporous resin. Despite prolonged exposure to organic solvent, this resi
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Until recently, resins were used primarily for peptide and oligonucleotide synthesis. Recent advances in combinatorial chemistry have fostered increased acceptance of resins as supports for the synthesis of small molecule libraries. The methodology for selecting a resin bead that is ideal for the so