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Solid phase synthesis of peptide hydroxamic acids on poly(ethylene glycol)-based support

✍ Scribed by Cal, Marta; Jaremko, Mariusz; Jaremko, Łukasz; Stefanowicz, Piotr


Book ID
118766365
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
616 KB
Volume
19
Category
Article
ISSN
1075-2617

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📜 SIMILAR VOLUMES


Solid phase synthesis of peptide hydroxa
✍ Jack J. Chen; Arno F. Spatola 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 225 KB

The synthesis of peptide hydroxamic acids has been performed on a solid support. A carboxyl group of a peptide synthesized on/xTa-methylbenzhydrylamin¢ (pMBHA) resin was converted to a hydroxamate functional group by condensing with NH2OBzl, which was found preferable to NH2OtBu or NH2OTrt. The hydr