Solid phase synthesis of peptide hydroxamic acids on poly(ethylene glycol)-based support
✍ Scribed by Cal, Marta; Jaremko, Mariusz; Jaremko, Łukasz; Stefanowicz, Piotr
- Book ID
- 118766365
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 616 KB
- Volume
- 19
- Category
- Article
- ISSN
- 1075-2617
- DOI
- 10.1002/psc.2466
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📜 SIMILAR VOLUMES
The synthesis of peptide hydroxamic acids has been performed on a solid support. A carboxyl group of a peptide synthesized on/xTa-methylbenzhydrylamin¢ (pMBHA) resin was converted to a hydroxamate functional group by condensing with NH2OBzl, which was found preferable to NH2OtBu or NH2OTrt. The hydr
The liquid-phase synthesis of protected peptide hydrazides can be suitably per \_ formed on modified poly(ethylene glycol) supports containing benzyl-, p-benzyloxybenzyl-, and tert-alkyl-oxycarbonylhydrazide anchoring groups.