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Solid-Phase Synthesis of Peptide and Glycopeptide Thioesters through Side-Chain-Anchoring Strategies

✍ Scribed by Simon Ficht; Richard J. Payne; Richard T. Guy; Chi-Huey Wong


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
681 KB
Volume
14
Category
Article
ISSN
0947-6539

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## Abstract Many naturally occurring peptide acids, e.g., somatostatins, conotoxins, and defensins, contain a cysteine residue at the C‐terminus. Furthermore, installation of C‐terminal cysteine onto epitopic peptide sequences as a preliminary to conjugating such structures to carrier proteins is a