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Solid-Phase Synthesis of Oligosaccharides: Construction of a Dodecasaccharide

✍ Scribed by K. C. Nicolaou; Nobuhide Watanabe; Jim Li; Joaquín Pastor; Nicolas Winssinger

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 146 KB
Volume: 37
Category: Article
ISSN: 0044-8249
DOI: 10.1002/(sici)1521-3773(19980619)37:11<1559::aid-anie1559>3.0.co;2-e

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✦ Synopsis

Complicated oligosaccharides such as dodecasaccharide 1 can be constructed by a new solid-phase strategy. The attachment to the polymeric support (gray sphere) is through a photolabile linker (structure I), and thioglycosides serve as carbohydrate donors. Bn=benzyl, Bz=benzoyl.

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