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Solid-Phase Synthesis of Imidazo[1,2-a]pyridine Using Sodium Benzenesulfinate as a Traceless Linker

✍ Scribed by Chen, Yu; Lam, Yulin; Lai, Yee-Hing


Book ID
120600385
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
84 KB
Volume
4
Category
Article
ISSN
1523-7060

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Solid-phase synthesis of imidazo[1,2-a]p
✍ Saı̈d El Kazzouli; Sabine Berteina-Raboin; Abderrahim Mouaddib; GΓ©rald Guillaume πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 French βš– 409 KB

The synthesis of imidazo [1,2-a]pyridine and imidazo[1,2-a]pyrimidine derivatives by condensation between an a-bromoketone bound to solid support and various 2-aminopyridine or 2-aminopyrimidine derivatives was described. Either an acid labile linker or a base labile linker was used in this study.