Solid phase synthesis of hydantoin libra
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Sang Woong Kim; Sang Youl Ahn; Jong Sung Koh; Jin Ho Lee; Seonggu Ro; Hae Yeon C
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Article
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1997
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Elsevier Science
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French
⚖ 165 KB
The variety of N, N-disubstituted hydantoin libraries were constructed using derivatives of amino acids, aromatic aldehydes, and isocyanates. The cyclization step of hydantoin was a novel, fast, and clean reaction and completed within five minutes to I hour with neat diisopropylamine. All library co