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Solid-phase synthesis of “head-to-tail” cyclic peptides via lysine side-chain anchoring

✍ Scribed by Jordi Alsina; Francesc Rabanal; Ernest Giralt; Fernando Albericio

Publisher: Elsevier Science
Year: 1994
Tongue: French
Weight: 385 KB
Volume: 35
Category: Article
ISSN: 0040-4039
DOI: 10.1016/0040-4039(94)88531-1

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## Abstract Many naturally occurring peptide acids, e.g., somatostatins, conotoxins, and defensins, contain a cysteine residue at the C‐terminus. Furthermore, installation of C‐terminal cysteine onto epitopic peptide sequences as a preliminary to conjugating such structures to carrier proteins is a