๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Solid phase synthesis of chiral 2-amino-benzimidazoles

โœ Scribed by Jinbo Lee; Amanda Doucette; Noel S Wilson; John Lord

Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
145 KB
Volume
42
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Solid phase synthesis of benzimidazoles
Solid phase synthesis of benzimidazoles
โœ Gary B. Phillips; Guo Ping Wei ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 204 KB
Solid-phase synthesis of substituted ben
Solid-phase synthesis of substituted benzimidazoles
โœ David Tumelty; Matthias K. Schwarz; Kathy Cao; Michael C. Needels ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 216 KB

A solid-phase synthesis of benzimidazoles, substituted on the aromatic ring by a variety of groups or atoms, is described. Intermediate 3, derived from the acylation of a resin-bound secondary amine with Fmoc-glycine, was elaborated via nucleophilic displacement with substituted o-halonitroarenes to

Solid-Phase Synthesis of 2-Amino-5-sulfa
Solid-Phase Synthesis of 2-Amino-5-sulfanylthiazoles
โœ Marie Grimstrup; Florencio Zaragoza ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 148 KB ๐Ÿ‘ 2 views

A solid-phase synthesis that provides easy access to 2-amino-5-sulfanylthiazoles with variable substituents at C-2, C-4, and C-5 has been developed. The key step of this synthesis is a new C-sulfanylation of resin-bound 2-aminothiazoles by mixtures of various sulfur-containing building blocks and io

Liquid-phase synthesis of 2-(alkylthio)
Liquid-phase synthesis of 2-(alkylthio) benzimidazoles
โœ Chih-Ming Yeh; Chung-Ming Sun ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 244 KB

An efficient liquid-phase synthesis of 2-alkylthio-5-carbamoylbenzimidazoles 1 is described. Immobilized ofluoronitrobenzene 2 undergoes nucleophilic addition of primary amine to afford o-nitroaniline derivatives 3. Subsequent reduction of the aromatic nitro group followed by cyclization gives a PEG