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Solid-phase synthesis of benzoxazoles via mitsunobu reaction

โœ Scribed by Fengjiang Wang; James R. Hauske

Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
218 KB
Volume
38
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

AIbslBlmL-2-Amidophenol attached to a solid support can be converted to the corresponding benzoxazole by treatment with tdphenylphosphine and diathyl azodicarboxylate in THF at room temperature in high yield and purity. ยฉ 1997 l~lsevk~ ~ยข~mcยข Lt(L The synthesis and screening of small molecule combinatorial libraries has become an important new technology for drug discovery. I A convenient format for the generation of these libraries is the synthesis of

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